Personal profile

Jiang Shengwei, Associate Professor and master supervisor, Department of Human Anatomy. In 2014, he graduated from Xiangya Medical School, Central South University, majoring in Preventive Medicine, and received his Bachelor's degree in Medicine. In 2017, he graduated from the School of Public Health of Xiamen University with a Master's degree in Translational medicine. In 2021, he graduated from Tsinghua University, Tsinghua Berkeley Shenzhen College, majoring in Precision Medicine and Public Health, and received his M.D. degree. From 2021 to 2023, he conducted postdoctoral research at Shenzhen University General Hospital. In October 2023, he was introduced to the post and selected into the "Yi Xian Scholars" program. His main research directions are: 1) Organoid preparation and application based on microfluidic technology; 2) Toxicological assessment and application development of nanomaterials; 3) Tissue regeneration based on organoid technology; 4) Clinical precision medicine application based on organoid technology. He is the lead author of Cell Reports Medicine (2020), Nature Machine Intelligence (2020), Advanced Materials (2023), and Advanced Healthcare Materials (2023, Cover paper) and other high-level academic journals published more than 10 papers. He presided over two scientific research projects, including the National Nature Youth Project and the postdoctoral Foundation project.

Academic achievement

Representative treatise

1. Jiang S, Zhao H, Zhang W,  et al. An Automated Organoid Platform with Inter-organoid Homogeneity and Inter-patient Heterogeneity. Cell Reports  Medicine. 2020, 1(9): 100161. (IF:14.3, District 1, Chinese Academy of Sciences)
2. Ye L, Jiang S (co-first author), Hu J,  et al. Induction of Metabolic Reprogramming in Kidney by Singlet Diradical Nanoparticles[J]. Advanced Materials, 2023:  2301338. (IF:29.4, District 1, Chinese Academy of Sciences)
3. Jiang S, Deng T, Cheng H,  et al. Macrophage-organoid co-culture model for identifying treatment strategies against macrophage-related gemcitabine  [J]. Journal of Experimental & Clinical Cancer Research, 2023, 42(1): 199. (IF:11.3, District 1, Chinese Academy of Sciences)
4. Jiang S, Liu W, Shi D,  et al. Black Phosphorus as a Targeting PPAR‐γ Agonist to Reverse Chemoresistance in Patient‐derived Organoids, Mice, and Pancreatic Tumor Cells[J]. Advanced Healthcare Materials, 2023: 2301324. (IF:10, District 1, Chinese Academy of Sciences)
5. Yong W, Mengqi J, Jiang S (co-first author),  et al. Augmenting Vascular Disease Diagnosis by Vasculature-aware Unsupervised Learning. Nature Machine Intelligence.  2020, 2(6): 337-346. (co-first author) (IF:23.8, District 1, Chinese Academy of Sciences)
6. He C, Ruan F, Jiang S (co-first author), et al. Black Phosphorus Quantum Dots Cause Nephrotoxicity in Organoids, Mice,  and Human Cells. Small, 2020, 16(22): 2001371. (IF:13.3, District 1, Chinese Academy of Sciences)
7. Zeng L. Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal cancer  organoids. Cancer Biology & Medicine, 2021, 18(2): 1-31. (Corresponding author) (IF:5.5, District 2, Chinese Academy of Sciences)
8. Zhang W, Li D, Jiang S (co-first author),  et al. Microfluidic droplets as structural templates for Matrigel to enable 1-week large organoid modeling. Chemical  Engineering Science, 2021: 116632. (co-first author) (IF:4.7, Second District, Chinese Academy of Sciences)
9. Jiang S, Lin Y, Yao H,  et al. The role of unfolded protein response and ER-phagy in quantum dots-induced nephrotoxicity:  an in vitro and in vivo study. Archives of Toxicology. 2018(1): 1-14. (IF:6.1, Subclass 1 Region, Chinese Academy of Sciences)
10. He C#, Jiang S# (co-first author), Jin H#,  et al. Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated  cancer-specific cytotoxicity. Biomaterials, 2016, 83:102-114. (co-first author) (IF:14, 1st District, Chinese Academy of Sciences)
11. He C#, Jiang S# (co-first author), Lin Y, Yao H,  et al. Endoplasmic reticulum stress mediates inflammatory response triggered by ultra-small superparamagnetic iron oxide nanoparticles in hepatocytes. Nanotoxicology. 2018, 12(10): 1198-1214. (IF:5.0, District 2, Chinese Academy of Sciences)
12. He C#, Jiang S# (co-first author), et al. High-content analysis for mitophagy response to nanoparticles:  A potential sensitive biomarker for nanosafety assessment. Nanomedicine. 2019, 15(1): 59-69. (IF:5.4, Second District, Chinese Academy of Sciences)

Award honor

He is the lead author of Cell Reports Medicine (2020), Nature Machine Intelligence (2020), Advanced Materials (2023), and Advanced Healthcare Materials (2023, Cover paper) and other high-level academic journals published more than 10 papers. He presided over two scientific research projects, including the National Nature Youth Project and the postdoctoral Foundation project.