Personal profile

Dr. Li Ming is a professor and doctoral supervisor of Zhongshan School of Medicine, Sun Yat-sen University. National overseas high-level talent introduction, Sun Yat-sen University 100 talent program young outstanding talent introduction, was employed by Sun Yat-sen University \"Yixian scholars Program\" outstanding scholar post. He received his PhD in entomology from Auburn University in 2014. He joined Sun Yat-sen Medical College of Sun Yat-sen University in July 2023. He has published 46 SCI papers, including Proceedings of the National Academy of Sciences, eLife, Nature communications and other well-known journals, and has constructed 700+ transgenic insect strains.
A pest is an organism that poses a competitive threat to humans. Including medically important mosquitoes, ticks, flies, bugs, etc., as well as important aphid, mites, butterflies, moths in agriculture and forestry, these harmful organisms endanger human health and life safety, causing huge economic losses.
The research group integrates entomology, genomics, genetics, molecular biology and genetic engineering, and 1) constructs a new pest (medical and agricultural) research platform based on transgenic and gene editing technologies; 2) Explore/explore the function of pest genes and the interaction mechanism with viruses, symbiotic bacteria, etc.; 3) Develop new pest population replacement and population control technologies to reduce the harm caused by pests to human health and reduce economic losses.

Academic achievement

Representative academic works

1.Ming Li, Xuechun Feng, William R Reid, Fang Tang, Nannan Liu. Multiple-P450 Gene Co-Up-Regulation in the Development of Permethrin Resistance in the House Fly, Musca domestica. 2023. International Journal of Molecular Sciences

https://www.mdpi.com/1422-0067/24/4/3170

2.Meng-meng Wu, Xu Chen, Qing-xuan Xu, Lian-sheng Zang, Su Wang, Ming Li （co-corresponding author)*, Da Xiao*. Melanin Synthesis Pathway Interruption: CRISPR/Cas9-mediated Knockout of dopa decarboxylase (DDC) in Harmonia axyridis (Coleoptera: Coccinellidae).  2022. Journal of Insect Science.

https://academic.oup.com/jinsectscience/article/22/5/1/6694719

3.Ming Li#, Ting Yang#, Michelle Bui, Stephanie Gamez, Tyler Wise, Nikolay P Kandul, Junru Liu, Lenissa Alcantara, Haena Lee, Jyotheeswara R Edula, Robyn Raban, Yinpeng Zhan, Yijin Wang, Nick DeBeaubien, Jieyan Chen, Hector M Sanchez C, Jared B Bennett, Igor Antoshechkin, Craig Montell, John M Marshall, Omar S Akbari. Suppressing mosquito populations with precision guided sterile males. 2021. Nature Communications.

https://www.nature.com/articles/s41467-021-25421-w

4.Ming Li, Ting Yang, Nikolay P Kandul, Michelle Bui, Stephanie Gamez, Robyn Raban, Jared Bennett, Gregory C Lanzaro, Hanno Schmidt, Yoosook Lee, John M Marshall, Omar S Akbari. Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti. 2020. eLife.

https://elifesciences.org/articles/51701

5.Ming Li (First author and co-corresponding author), Omar S Akbari, Bradley J White. Highly efficient site-specific mutagenesis in malaria mosquitoes using CRISPR. 2018. G3: Genes, Genomes, Genetics.

https://pubmed.ncbi.nlm.nih.gov/29233915/

6.Ming Li, Michelle Bui, Ting Yang, Christian S Bowman, Bradley J White, Omar S Akbari. Germline cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, Aedes aegypti. 2017. Proceedings of the National Academy of Sciences.

https://www.pnas.org/content/114/49/E10540

7.Ming Li, Lauren Yun Cook Au, Deema Douglah, Abigail Chong, Bradley J White, Patrick M Ferree, Omar S Akbari. Generation of heritable germline mutations in the jewel wasp Nasonia vitripennis using CRISPR/Cas9. 2017. Scientific Reports.

https://www.nature.com/articles/s41598-017-00990-3