Department:Department of Genetics and Cell Biology
E-mail:zhangf363@mail.sysu.edu.cn
Research direction:The research focuses on the mechanism of phase separation and chromatin three-dimensional structure regulating cancer initiation and recurrence.
Personal profile
2023.5 -
Associate Professor, Sun Yat-sen College of Medicine, Sun Yat-sen University
2021-2023
Associate Researcher, The First People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
2017-2021.
Assistant Researcher, First People's Hospital Affiliated to Shanghai Jiao Tong University/Shanghai Jiao Tong University School of Medicine
2014-2017.
Postdoctoral Fellow, Shanghai Institute of Hematology/Shanghai Jiaotong University School of Medicine
2009-2014.
Master's degree, Shanghai Jiaotong University School of Medicine/Shanghai Institute of Hematology
The research focuses on the mechanism of phase separation and chromatin three-dimensional structure regulating cancer initiation and recurrence. In the past five years, he has been the first or corresponding author in Circulation, Cell reports, Journal of Translational Medicine, Journal of Leukocyte Biology, Cell Death & Disease Published research results in international journals, etc., and obtained 2 national invention patents. As the project leader, he has presided over 7 national, provincial, municipal and school projects, including 2 projects of National Natural Science Foundation and 1 project of Shanghai Talent Plan.
Academic achievement
- Huijing Yu#, Fang Zhang#, Pengyi Yan#, Shasha Zhang#, Yingmei Lou, Zilong Geng, Zixuan Li, Yan Zhang, Yuejuan Xu, Yanan Lu, Chen Chen, Dao Wen Wang, Wei Zhu, Xinyang Hu, Jian'an Wang, Tao Zhuang, Yuzhen Zhang, Gengze Wu, Junling Liu, Chunyu Zeng, William Pu, Kun Sun, Bing Zhang. LARP7 Protects Against Heart Failure by EnhancingMitochondrial Biogenesis. Circulation. 2021 May 18;143(20):2007-2022. (# co-first author)
- Fang Zhang#, Pengyi Yan#, Huijing Yu#, Huangying Le#, Zixuan Li, Jiahuan Chen, Xiaodong Liang, Shiyan Wang, Weiting Wei, Li Liu, Yan Zhang, Xing Ji, Anyong Xie, Wantao Chen, Zeguang Han, William T. Pu, Sun Chen, Yingwei Chen, Kun Sun, Baoxue Ge, Bing Zhang. LARP7 is a BRCA1 ubiquitinase substrate and regulates genome stability and tumorigenesis, Cell reports 2020 Jul 28;32(4):107974.
- Kening Li, Yuxin Du, Dong-Qing Wei, Fang Zhang. CEBPE expression is an independent prognostic factor for acute myeloid leukemia, Journal of Translational Medicine. 2019 Jun 4;17(1):188.(corresponding author) .
- Wenhua Yu#, Fang Zhang#, Shiyan Wang, Yi Fu, Jiahuan Chen, Xiaodong Liang, Huangying Le, William T Pu, Bing Zhang. Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis, Cell Death & Disease, 2017 Apr13;8(4): e2744. (# co-first author)
- Fang Zhang#, Yong Lan Zhu#, Wang Long Deng, Jiang Zhu, Ji Zhang. Activation of G0S2 is coordinated by recruitment of PML/RARα and C/EBPε to its promoter during ATRA-induced APL differentiation. Journal of Leukocyte Biology. 2017 Mar;101(3):655-664.
Award honor
In the past five years, he has been the first or corresponding author in Circulation, Cell reports, Journal of Translational Medicine, Journal of Leukocyte Biology, Cell Death & Disease Published research results in international journals, etc., and obtained 2 national invention patents. As the project leader, he has presided over 7 national, provincial, municipal and school projects, including 2 projects of National Natural Science Foundation and 1 project of Shanghai Talent Plan.