Personal profile

Chen Feng is an associate professor and master tutor of Sun Yat-sen School of Medicine, Sun Yat-sen University. In 2010, he graduated from the School of Life Science, Huazhong University of Science and Technology with a Bachelor of Science degree. In 2017, he graduated from the School of Life Sciences of Wuhan University with a Doctor of Science degree. From 2018 to 2023, he worked as a postdoctoral fellow and special associate researcher in Zhongshan Medical College.

His research focuses on the relationship between gene expression and phenotype. The main findings include: 1) The mechanism by which competition between virus and host for translation resources affects host phenotype; 2) Restriction of expression noise is a key factor in maintaining phenotypic homeostasis. The research results have been published as first/corresponding author in Nature Ecology & Evolution, Molecular Biology and Evolution, iScience, et al. He presided over four projects including the National Natural Science Foundation, Youth Project and Guangdong Province Project, and participated in a national key research and development young scientist project as a backbone.

If you are interested in genetics, bioinformatics, microbiology or cell biology, please contact Dr. Chen Feng at chenfeng5@mail.sysu.edu.cn

Academic achievement

Representative publications (for a complete list of publications, see https://orcid.org/0000-0002-5588-1082)

1. Feng Chen#, Zizhang Li#, Xiaoyu Zhang, Peng Wu, Wenjing Yang, Junnan Yang, Xiaoshu Chen, Jian-Rong Yang*;  Phylogenetic comparative analysis of single-cell transcriptomes reveals constrained accumulation of gene expression  heterogeneity during clonal expansion;  Molecular Biology and Evolution;  2023; 40(5): msad113.
2. Feng Chen*, Jian-Rong Yang*;  Distinct codon usage bias evolutionary patterns between weakly and strongly virulent respiratory viruses, iScience,  2022, 25(1): 103682.
3. Feng Chen, Peng Wu, Shuyun Deng, Heng Zhang, Yutong Hou, Zheng Hu, Jianzhi Zhang*, Xiaoshu Chen*, Jian-Rong Yang*;  Dissimilation of synonymous codon usage bias in virus-host coevolution due to translational selection;  Nature Ecology & Evolution;  2020; 4(3): 589-600.
4. Feng Chen, Fengling Lai, Majing Luo, YuSan Han, Hanhua Cheng*, Rongjia Zhou*;  The genome-wide landscape of small insertion and deletion mutations in Monopterus albus. Journal of Genetics and  Genomics, 2019, 46(2): 75-86.

Scientific research project

1. Project of National Natural Science Foundation of China, 2023/01-2026/12,540,000
2. National Natural Science Foundation Youth Project, 2012/01-2023/12, 240,000
3. National Key Research and Development Program for Young Scientists, 2022/12-2027/11 million (backbone/participation)
4. Project of Natural Science Foundation of Guangdong Province, 2023/01-2025/12, 100,000 yuan
5. Guangzhou Science and Technology Planning Project, 2020/03-2020/03, 50,000