Personal profile

Jiang Meihua is a professor, doctoral supervisor and master supervisor of Sun Yat-sen School of Medicine, Sun Yat-sen University. Member of Cell Therapy Branch of Guangdong Medical Association, Vice Chairman of Youth Committee, member of Chinese Anatomical Society, member of Guangdong Anatomical Society. In 2010, he graduated from Kyung Hee University, South Korea, and received his doctor's degree under the supervision of Youngsook Son, a famous stem cell expert in South Korea. In 2010, he joined Zhongshan School of Medicine, Sun Yat-sen University.
He is mainly engaged in research on mechanisms related to adult Stem Cell transplantation and tissue regeneration and repair, and has published more than 20 papers in academic journals such as Nature Medicine, Cell Rescerch, Biomaterials, Journal of Neuroscience, Stem Cells, etc. More than 900 citations. The main academic contributions are as follows: 1) Confirmed the regulatory mechanism of mobilizing endogenous neural stem cells and bone marrow mesenchymal stem cells to participate in injury repair; 2) Research on targeted extension of axons and mechanism of nerve regeneration; 3) Adult stem cell marker Nestin was used to isolate and identify heart, kidney and testicular mesenchymal stem cells, and confirm their role and mechanism in tissue regeneration and repair, as well as their role in the aging process, providing an important scientific basis for revealing the developmental origin of tissue stem cells and clinical transformation applications. Presided over two National Natural Science Foundation projects, Guangzhou People's livelihood science and technology plan projects, Guangdong Province science and technology plan projects, etc. As a backbone, he participated in national key research and development programs, key projects of National Natural Science Foundation, major science and technology projects of Guangdong Province, National major research programs/key support projects, etc., with research funding of more than 10 million yuan, obtained 3 authorized patents, and applied for 2 PCT patents. Participate in the compilation of medical anatomy, format anatomy and other teaching materials.

Academic achievement

1. Xie D, Liao Y, Wu B, Chen Y, Lin W, Lu D, Gao S, Zhu S, Peng C, Jiang MH*.Cardiac Nestin+ cells derived from early stage of dilated cardiomyopathy enhanced the survival of the doxorubicin-injured cardiac muscle HL-1 cells. Int Heart J. 2018，59(1):180-189. IF:1.826
2. Zang ZJ, Fang YQ, Ji SY, Gao Y, Zhu YQ, Xia TT, Jiang MH, Zhang YN.Formaldehyde Inhibits Sexual Behavior and Expression of Steroidogenic Enzymes in the Testes of Mice. J Sex Med. 2017，14(11):1297-1306. IF:3.339
3. Yang L＃, Li G, Ye J, Lu D, Chen Z, Xiang AP, Jiang MH*. Substance P enhances endogenous neurogenesis to improve functional recovery after spinal cord injury. Int J Biochem Cell Biology. 2017, 1; 89:110-119. IF: 3.247
4. Zhang M＃, Jiang MH＃, Kim DW, Ahn W, Chung E, Son Y, Chi G. Comparative Analysis of the Cell Fates of Induced Schwann Cells from Subcutaneous Fat Tissue and Naïve Schwann Cells in the Sciatic Nerve Injury Model.Biomed Res Int. 2017, 2017:1252851. IF: 2.476
5. Zang ZJ＃, Wang J＃, Chen Z＃, Zhang Y＃, Gao Y, Su Z, Tuo Y, Liao Y, Zhang M, Yuan Q, Deng C, Jiang MH*, Xiang AP*.Transplantation of CD51+ stem Leydig cells: A new strategy for the treatment of testosterone deficiency. Stem cells2017, 35(5):1222-1232. IF: 5.902
6. Zang Z＃, Li S, Lin Y, Li X, Li Y, Qin Y, Wang H, Jiang MH*, Zhu L＊. Pentoxifylline Prevents Driamycin-Induced Myocardial Fibrosis and Apoptosis in Rats.Int Heart J. 2015, 2;56(6):651-5   IF:1.826
7. Jiang MH#, Li G#, Liu J#, Liu L, Wu B, Huang W, He W, Deng C, Wang D, Li C, Lahn BT, Shi C*, Xiang AP*.Nestin(+) kidney resident mesenchymal stem cells for the treatment of acute kidney ischemia injury. Biomaterials. 2015, 50:56-66. IF：8.806
8. Li WQ#, Huang LH#, Lin WY#, Ke Q, Chen R, Lai XQ, Wang XY, Zhang JF, Jiang MH, Huang WJ, Wang T, Yang XS, Chen Y, Song W*, Xiang AP*. Engraftable neural crest stem cells derived from cynomolgus monkey embryonic stem cells. Biomaterials, 2015, Jan;39:75-84. IF：8.806
9. Jiang MH#, Cai B#, Tuo Y#, Wang J, Zang ZJ, Tu X, Gao Y, Su Z, Li W, Li G, Zhang M, Jiao J, Wan Z, Deng C, Lahn BT, Xiang AP*.Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunctionCell Res. 2014, 24(12):1466-85. IF:15.393
10. Tang S#, Zhu J#, Xu Y, Xiang AP, Jiang MH*, Quan D*.The effects of gradients of nerve growth factor immobilized PCLA scaffolds on neurite outgrowth in vitro and peripheral nerve regeneration in rats.Biomaterials. 2013, 34(29):7086-9. IF:8.806
11. Jiang MH#, Lim JE, Chi GF, Ahn W, Zhang M, Chung E*, Son Y*. Substance P reduces apoptotic cell death possibly by modulating the immune response at the early stage after spinal cord injury. Neuroreport. 2013, 24(15):846-51.IF:1.266
12. Jiang MH#, Chung E#, Chi GF, Ahn W, Lim JE, Hong HS, Kim DW, Choi H, Kim J, Son Y*. Substance P induces M2-type macrophages after spinal cord injury.Neuroreport.2012, 23(13):786-92. IF: 1.266
13. Kang J#,Jiang MH, Min HJ, Jo EK, Lee S, Karin M, Yune TY, Lee SJ*. IKK-β-mediated myeloid cell activation exacerbates inflammation and inhibits recovery after spinal cord injury. Eur J Immunol , 2011, 41(5) : 1266-77. IF: 4.248
14. Chi GF#, Kim MR, Kim DW, Jiang MH, Son Y*. Schwann cells differentiated from spheroid-forming cells of rat subcutaneous fat tissue myelinate axons in the spinal cord injury.Exp. Neurol.2010, 222（2）: 304-17. IF: 4.483
15. Hong HS#, Lee J, Lee E, Kwon YS, Lee E, Ahn W, Jiang MH, Kim JC, Son Y*. A new role of substance P as an injury-inducible messenger for mobilization of CD29(+) stromal-like cells. Nat Med. 2009, 15（4），425-35. IF: 32.621
16. Yune TY#, Lee JY#, Jiang MH,Kim DW, Choi SY, Oh TH*.Systemic administration of PEP-1-SOD1 fusion protein improves functional recovery by inhibition of neuronal cell death after spinal cord injury. Free Radic. Biol.Med.2008，45（8），1190-1200. IF: 6.020
17. Yune TY#, Lee JY, Jung GY, Kim SJ, Jiang MH, Kim YC, Oh YJ, Markelonis GJ, Oh TH*. Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury.J Neurosci.2007，18，27（29），7751-61. IF: 5.97

Textbook monograph

Medical Anatomy (Second edition), People's Publishing House
Format Anatomy (41st edition), Shandong Science and Technology Press