Personal profile

Du Yanhua, female, Professor of pharmacology and doctoral supervisor, Zhongshan School of Medicine, Sun Yat-sen University. In 2007, he was jointly trained by Sun Yat-sen University and Michigan State University. In December 2008, he was employed as an associate professor in Zhongshan Medical College of Sun Yat-sen University as a talent introduced by Sun Yat-sen University. In December 2013, he was promoted to professor. In recent years, he has been committed to the research of cardiovascular pharmacology and pathophysiology, mainly focusing on the role of ion channels in cardiovascular and cerebrovascular diseases. At present, he has presided over a number of National Natural Science Foundation projects, provincial and ministerial level and other fund projects. In 2010, he was selected as the training object of the \"Thousand Hundred and Ten Projects\" of Guangdong Provincial colleges and universities, in 2011, he was awarded the title of the first batch of \"Guangzhou Pearl River Science and Technology Star\", in 2014, he was selected as \"Sun Yat-sen University Excellent Young Teacher Training Program\", and in 2016, he was awarded the Shi Weiya Young Pharmacologist Award of Chinese Pharmacological Society. As one of the main adults, he won the second prize of Natural Science Award of the Ministry of Education, the second prize of China Medical Science and Technology Award and the first prize of Science and Technology Award of Guangdong Province.

Academic achievement

Representative paper

1. Inhibition of TMEM16A Improves Cisplatin-induced Acute Kidney Injury Via Preventing DRP1-mediated Mitochondrial Fission. Acta Pharmacologica Sinica, 2023.
2. DDR1 activation in macrophage promotes IPF by regulating NLRP3 inflammasome and macrophage reaction. International Immunopharmacology, 2022.
3. Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl
   concentration. Br J Pharmacol, 2022.
4. TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner. Acta Pharmaceutica Sinica B, 2021.
5. ClC-3 Defificiency Impairs the Neovascularization Capacity of Early Endothelial Progenitor Cells by Decreasing CXCR4/JAK-2 Signalling. Can J Cardiol, 2019.
6. ClC-3 promotes angiotensin II-induced reactive oxygen species production in endothelial cells by facilitating Nox2 NADPH oxidase complex formation. Acta Pharmacologica Sinica, 2018.
7. Endophilin A2 protects H2O2-induced apoptosis by blockade of Bax translocation in rat basilar artery smooth muscle cells. J Mol Cell Cardiol, 2016. 
8. ClC-3 deficiency prevents atherosclerotic lesion development in ApoE-/- mice.  J Mol Cell Cardiol, 2015. 
9. Deficiency of volume-regulated ClC-3 chloride channel attenuates cerebrovascular remodelling in DOCA-salt hypertension. Cardiovasc Res, 2013. 
10. ClC-3 Deficiency Prevents Apoptosis Induced by Angiotensin II in Endothelial Progenitor Cells via Inhibition of NADPH Oxidase. Apoptosis, 2013.  
11. A new role for caveolin-1: regulation of guanosine triphosphate cyclohydrolase I and tetrahydrobiopterin in endothelial cells.  Hypertension, 2009. 
12. Endothelial-Specific GTP Cyclohydrolase I Overexpression Attenuates Blood Pressure Progression in Low Renin Hypertension.  Circulation, 2008. 

Academic part-time job

Standing member of Teaching and Science Popularization Committee of Chinese Pharmacological Society, Standing member of Cardiovascular Committee of Guangdong Pharmacological Society, standing member of Pharmacological Education Committee of Guangdong Pharmacological Society